Handbook of Pharmaceutical Excipients
(5th edition)
- A useful resource for industrial pharmacists
- Pharmaceutical excipients are the inactive substances that are added to a drug formulation along with the active ingredient(s) to aid in its manufacture, administration, absorption, or stability.
- Excipients play a crucial role in the formulation of pharmaceutical products. They help in achieving the desired properties of the dosage form, such as its shape, size, hardness, and disintegration time.
- Excipients can improve the bioavailability of drugs by enhancing their solubility, permeability, and stability.
- Excipients can protect the active ingredient from degradation, prevent microbial growth, and mask unpleasant tastes or odors.
- Excipients can be categorized based on their functional properties, such as fillers, binders, disintegrants, lubricants, preservatives, flavors etc.
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