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  1. Propranolol does not block the mydriatic action of adrenaline.
  2. Propranolol can impair carbohydrate tolerance in pre-diabetics but prolongs insulin hypoglycaemia.
  3. In Raynaud’s disease, Propranolol administration exacerbates the condition.
  4. β-adrenergic blockers are not indicated in vasospastic angina pectoris (prinzmetal / variant / rest angina). Coronary vasodilators (NG) and CCBs are agents of choice in this kind of angina.
  5. Stable or typical or classical angina is relieved promptly with rest or nitroglycerin while unstable angina will not respond to this strategy and requires hospital admission and more aggressive therapy to prevent its advance into MI & death.
  6. Esmolol is an ultra-short acting cardioselective β-adrenergic blocker with suitability for intra-operative use.
  7. The basis for use of β-adrenergic blockers in congestive heart failure (CHF) is that they counteract deleterious effect of sympathetic overactivity on the myocardium.
  8. Atenolol is a β-adrenergic blocker that is primarily eliminated unchanged by renal excretion.
  9. Carvedilol is a β-adrenergic blocker that has additional α1-blocking, vasodilator and antioxidant properties.
  10. In hyperthyroidism, β adrenergic blockers are used for rapid control of certain symptoms while awaiting response to carbimazole.