Note: Answer keys are given at the end of this post. You can get these MCQs in PDF document. The link is shared at the end of this post.
a- suitable for irritating substances
b- ideal for high molecular weight peptide drugs
c- unsuitable for oily substances
d- require strict aseptic techniques
e- all of the options are true
62. The following is(are) considered to be topical dosage form(s);
a- patches
b- eye drops
c- ear solutions
d- nasal drops
e- all of the above
63. The main mechanism(s) of absorption from GIT for exceptionally large size molecules of drug moieties is(are);
a- passive diffusion
b- facilitated diffusion
c- active transport
d- endocytosis
e- both c & d
64. Vitamin B12 is absorbed from the GIT by one of the following mechanisms;
a- passive diffusion
b- facilitated diffusion
c- active transport
d- endocytosis
e- any of the above
65. All of the following factors may affect the absorption of drugs except;
a- pH of the environment
b- contact time at absorption surface
c- perfusion of absorption site
d- expression of P-glycoprotein
e- none of the above
66. The recommended daily amount (RDA) of vitamin B-12 for adults is;
a- 2.4 micrograms
b- 240 micrograms
c- 500 micrograms
d- 1000 micrograms
e- 2000 micrograms
67. The injectable form(s) of vitamin B12 that is(are) used to treat deficiency of this vitamin is;
a- hydroxocobalamin
b- adenosylcobalamin
c- cyanocobalamin
d- methylcobalamin
e- both b & d
68. If 50 mg of a drug is given orally, and only 30 mg of it reaches the blood in unchanged form, then its bioavailability will be;
a- 30%
b- 50%
c- 60%
d- 70%
e- 80%
69. Bioavailability can be determined as;
a- AUC(oral)/AUC(i.v)
b- AUC(oral)/AUC(i.v)x100
c- AUC(i.v)/AUC(oral)
d- AUC(i.v)/AUC(oral)x100
e- all of the above
70. Drugs having the following chemical nature will effectively cross biological barriers and spaces, thus reaching their target site;
a- very hydrophilic
b- very lipophilic
c- largely lipophilic, some hydrophilicity
d- largely hydrophilic, some lipophilicity
e- equally hydrophilic & lipophilic
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Answer Keys
MCQ # - Correct option
61- e
62- e
63- d
64- d
65- e
66- a
67- a
68- c
69- b
70- c
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