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Note: Answer keys are given at the end of this post. You can get these MCQs in PDF document. The link is shared at the end of this post.

61. The following statement(s) is(are) true regarding intravenous mode of drug administration;
a- suitable for irritating substances
b- ideal for high molecular weight peptide drugs
c- unsuitable for oily substances
d- require strict aseptic techniques
e- all of the options are true

62. The following is(are) considered to be topical dosage form(s);
a- patches
b- eye drops
c- ear solutions
d- nasal drops
e- all of the above

63. The main mechanism(s) of absorption from GIT for exceptionally large size molecules of drug moieties is(are);
a- passive diffusion
b- facilitated diffusion
c- active transport
d- endocytosis
e- both c & d

64. Vitamin B12 is absorbed from the GIT by one of the following mechanisms;
a- passive diffusion
b- facilitated diffusion
c- active transport
d- endocytosis
e- any of the above

65. All of the following factors may affect the absorption of drugs except;
a- pH of the environment
b- contact time at absorption surface
c- perfusion of absorption site
d- expression of P-glycoprotein
e- none of the above




66. The recommended daily amount (RDA) of vitamin B-12 for adults is;
a- 2.4 micrograms
b- 240 micrograms
c- 500 micrograms
d- 1000 micrograms
e- 2000 micrograms

67. The injectable form(s) of vitamin B12 that is(are) used to treat deficiency of this vitamin is;
a- hydroxocobalamin
b- adenosylcobalamin
c- cyanocobalamin
d- methylcobalamin
e- both b & d

68. If 50 mg of a drug is given orally, and only 30 mg of it reaches the blood in unchanged form, then its bioavailability will be;
a- 30%
b- 50%
c- 60%
d- 70%
e- 80%

69. Bioavailability can be determined as;
a- AUC(oral)/AUC(i.v)
b- AUC(oral)/AUC(i.v)x100
c- AUC(i.v)/AUC(oral)
d- AUC(i.v)/AUC(oral)x100
e- all of the above

70. Drugs having the following chemical nature will effectively cross biological barriers and spaces, thus reaching their target site;
a- very hydrophilic
b- very lipophilic
c- largely lipophilic, some hydrophilicity
d- largely hydrophilic, some lipophilicity
e- equally hydrophilic & lipophilic



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Answer Keys
MCQ # - Correct option
61- e
62- e
63- d
64- d
65- e
66- a
67- a
68- c
69- b
70- c