Pharmacy Subjects MCQs with Answer Keys - MCQ # 71 to 80 - Part 8

www.pharmacymcqs.com

Note: Answer keys are given at the end of the MCQs.

71. All the following statements are correct regarding vitamin B12 except; 
a- can be stored in the liver for years
b- an essential water-soluble vitamin
c- requires haptocorrin to protect it from stomach acid
d- requires intrinsic factor for absorption
e- cannot be stored in the body

72. The most common and most important of all conjugation reactions of drug metabolism is;
a- sulfuric acid conjugation
b- acetic acid conjugation
c- amino acid conjugation
d- methylation
e- glucoronidation

73. Cytochrome P450 isozymes contains in them;
a- iron
b- cobalt
c- magnesium
d- copper
e- oxygen

74. One of the following isozymes is responsible for the vast majority of cytochrome-P450 catalyzed reactions;
a- CYP3A4 / 5
b- CYP2D6
c- CYP2C8 / 9
d- CYP1A2
e- CYP2C19

75. One of the following isozymes is not very susceptible to enzyme induction, which makes it free of the possibility of drug interaction;
a- CYP3A5
b- CYP2D6
c- CYP2C9
d- CYP1A2
e- CYP2C19




76. Glomerular filteration rate (GFR) in a normally functioning healthy renal system is;
a- 30 ml/min
b- 60 ml/min
c- 120 ml/min
d- 240 ml/min
e- 480 ml/min

77. The disintegration time (DT) of orally dispersible tablets (ODTs) is;
a- immediate upon contact
b- within half a minute
c- within a minute
d- within a minute and a half
e- within two minutes

78. A drug reaches its steady-state plasma concentration in about how many half-lives?
a- 2
b- 3
c- 4 to 5
d- 7
e- 10

79. The only determining factor of the time it takes to reach steady-state plasma drug concentration (tss) is;
a- rate of infusion
b- half-life
c- clearance
d- volume of distribution
e- dose of the drug 

80. If doses of a drug are given at its half-life, then 75% of the steady-state plasma concentration will be achieved with its;
a- 1st half-life
b- 2nd half-life
c- 3rd half-life
d- 4th half-life
e- 5th half-life

----------------------------------------------------------------------------

Watch the same set of MCQs solved plus discussed in the following video. Subscribe our YouTube channel for upcoming videos.

------------------------------------------------------ 

Answer Keys

MCQ # - Correct option

71- e

72- e

73- a

74- a

75- b

76- c

77- b

78- c

79- b

80- b