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Note: Answer keys are given at the end of the MCQs.

81. Concomitant administration of clopidogrel with omeprazole results in;

a- increased activity of clopidogrel
b- decreased activity of clopidogrel
c- no change of activity of clopidogrel
d- decreased activity of omeprazole
e- increased activity of omeprazole

82. If the half-life of a drug is 8 hours, then in how much time this drug is expected to reach its steady-state plasma concentration?
a- 12 hours
b- 18 hours
c- 26 hours
d- 32 hours
e- 48 hours

83. The only immunoglobulin that can cross the placenta and thus its presence in the fetus is indicative of immunity and not of infection by some pathogen is;
a- IgA
b- IgE
c- IgG
d- IgM
e- gamma globulin

84. All of the following are antitussives except;
a- levopropoxyphene
b- clophedianol
c- dextropropoxyphene
d- dextromethorphan
e- oxeladin

85. The response time of ligand-gated ion channels is;
a- few milliseconds
b- seconds to minutes
c- minutes to hours
d- hours to days
e- days to weeks




86. The response time of G-protein coupled receptors is;
a- few milliseconds
b- seconds to minutes
c- minutes to hours
d- hours to days
e- days to weeks

87. The response time of enzyme-linked receptors is;
a- few milliseconds
b- seconds to minutes
c- minutes to hours
d- hours to days
e- days to weeks

88. The response time of intracellular  receptors is;
a- few milliseconds
b- seconds to minutes
c- minutes to hours
d- hours to days
e- days to weeks

89. The family of receptors that undergoes autophosphorylation upon activation by a ligand is;
a- intra-cellular receptors
b- enzyme-linked receptors
c- G-protein coupled receptors
d- ligand-gated ion channels
e- autonomic NS receptors

90. One of the following is banned in the coating of pharmaceuticals in pharma industries for its health concern;
a- isopropyl alcohol
b- castor oil
c- EUDRAGIT
d- methylene chloride
e- titanium dioxide
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Answer Keys
MCQ # - Correct option
81- b
82- d
83- c
84- c
85- a
86- b
87- c
88- d
89- b
90- d