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Note: Answer keys are given at the end of the MCQs.

131. The catabolic enzyme, acetylcholinesterase is found in the following location(s) of the human body;

a- pre-synaptic membrane
b- post-synaptic membrane
c- red blood cell
d- both a and b
e- all of the above


132. One of the following is an irreversible acetylcholinesterase inhibitor and thus act as an indirect-acting cholinergic agonist;
a- pralidoxime
b- physostigmine
c- galantamine
d- echothiophate
e- edrophonium

133. Cyclopentolate is;
a- anti-muscarinic agent
b- ganglion-blocker
c- neuro-muscular blocker
d- cholinergic agonist
e- adrenergic antagonist


134. The following statements are correct about Edrophonium except one;
a- it is a reversible AChE inhibitor
b- it is eliminated via bile into feces
c- its duration of action 10 to 20 minutes
d- it actions are limited to the periphery
e- it is a quaternary amine


135. One of the following agents is used in the diagnosis of an autoimmune disease, myasthenia gravis;
a- edrophonium
b- physostigmine
c- neostigmine
d- pyridostigmine
e- galantamine





136. Kala Azar is;
a- visceral leishmaniasis
b- cutaneous leishmaniasis
c- visceral schistosomiasis
d- cutaneous schistosomiasis
e- cutaneous giardiasis

137. One of the following is useful as an adjunct in the quitting of smoking habit;
a- amphetamine
b- methylphenidate
c- dexmethylphenidate
d- varenicline
e- nicotine

138. One of the following statements is correct about varenicline (CHAMPIX), which is that one?
a- it is a partial agonist at nicotinic receptors in CNS
b- it is a full agonist at nicotinic receptors in CNS+PNS
c- it produces more euphoric effects than nicotine
d- it is safe generally and needs no patient monitoring
e- first-line agent in alcohol quitting

139. Hemolytic anemia is the adverse effect caused by which one of the following classes of drugs?
a- Aminoglycosides
b- Tetracyclines
c- Macrolides
d- Sulfonamides
e- Fluoroquinolones

140. Tramadol is a centrally acting analgesic that exerts its pharmacological effect via binding to;
a- mu-opioid receptors
b- kappa opioid receptors
c- delta-opioid receptors
d- zeta opioid receptors
e- all of the above

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Answer Keys
MCQ # - Correct option
131- e
132- d
133- a
134- b
135- a
136- a
137- d
138- a
139- d
140- a